History

Now called the Pediatric Heart Transplant Society (PHTS), the Pediatric Heart Transplant Study Registry was established in 1993 by a group of physicians who wanted to improve the lives of children who needed a heart transplant. The primary purposes of the organization was to establish and maintain a prospective, event driven database for heart transplantation, to encourage and stimulate basic and clinical research in the field of pediatric heart transplantation, and to promote new therapeutic strategies. The ultimate goal was to improve the lives of pediatric heart transplant recipients.

With more than 25 years of data collection, PHTS has produced over 120 abstract presentations and over 90 peer-reviewed manuscripts analyzing the continuum from pre-transplant risk factors to post-transplant morbidities which impact long-term survival after heart transplant in childhood. Information gained has significantly increased our understanding of pediatric heart transplantation and has allowed pediatric heart transplant doctors and nurses to help children after heart transplant live longer and have a better quality of life.

The Pediatric Heart Transplant Study (PHTS) was started by Dr. James Kirklin (cardiac surgeon), Dr. David Naftel (statistician), and Dr. Robert Morrow (pediatric cardiologist) at the University of Alabama at Birmingham in 1993. The registry was modeled after the adult version started three years prior called the CardioThoracic Research Database (CTRD) which has since closed. Dr. Morrow served as the president of the PHTS registry until 2001 at which point a formal election process was established to elect a new president and rotating committees every two years. Dr. Naftel served as the Director of the Data Coordinating Center (DCC) until May 2014 when he retired from UAB. Dr. Kirklin served as the study PI and in May 2014 he also became DCC Director following Dr. Naftel’s retirement.

PHTS Foundation
In 2010, the leadership of PHTS created a 501(c)3 not for profit known as the PHTS Foundation. This Foundation took the place of the previously known Finance Committee of PHTS. The PHTS Foundation was established to raise and administer funds to advance the science and treatment of children while listed for and following heart transplantation. The PHTS Foundation supports the work of the Pediatric Heart Transplant Society (PHTS). Learn more about the PHTS foundation.

Pediatric Heart Transplant Society
In January 2018 at the annual PHTS leadership meeting in Birmingham, Alabama, the leadership proposed to change the name of the registry from Pediatric Heart Transplant Study to Pediatric Heart Transplant Society. This was put to the membership for a vote and there was a unanimous vote to change the name. Shortly thereafter and after 24 years of the same logo, PHTS accepted submissions for new logo ideas and a new logo was voted on and selected in the summer of 2018.

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Historical
Research
PHTS Presidents
Form Revisions
July 9, 1992
Meeting minutes from July 1992 meeting of the Pediatric Heart and Lung Transplant Study Group
1992
Invitation to the November 1992 meeting in New Orleans of the Pediatric Heart and Lung Transplant Study Group
November 11,1992
List of guests invited to the November 1992 meeting of the Pediatric Heart and Lung Transplant Study Group
November 23,1992
Letter from Dr. Linda Addonizio on behalf of the Pediatric Heart and Lung Transplant Study Group to Dr. James Kirklin notifying him the group has chosen to go with UAB for development of the PHTS database mimicking the existing CTRD database.
January 1, 1993
PHTS Data Collection kicks off under the direction of Dr. William Robert Morrow. Additional staff at the Data Coordinating Center included Dr. James Kirklin, Dr. David Naftel, and Leslie Early.
April 2, 1993
Pediatric Heart and Lung Transplant Study Group meeting minutes
November 8, 1993
Pediatric Heart and Lung Transplant Study Group holds annual fall membership meeting in Atlanta, Georgia.
1994
Kaplan Meier from 1994 reporting on the first 208 patients enrolled in PHTS hand labeled by Dr. David Naftel.
January 1, 1996
First Major Form Revision
November 1996
Publication
Outcome of Cardiac Transplantation in Children: Survival in a Contemporary Multi-institutional Experience

Shaddy R, Naftel D, Boyle G, McGiffin D, Towbin J, Ring S, Pearce B, Addonizio L, Kirklin J, Morrow W,and the Pediatric Heart Transplant Study. Circulation. 1996 Nov 1;94(9 Suppl II):69-73.
July 1997
Publication
Predicting Outcome After Listing for Heart Transplantation in Children: Comparison of Kaplan-Meier and Parametric Competing Risk Analysis

McGiffin D, Naftel D, Kirklin J, Morrow W, Towbin J, Shaddy R, Alejos J, Rossi A, and the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 1997 Jul;16 (7):713-22.
July 1997
Publication
Survival and Risk Factors for Death after Cardiac Transplantation in Infants: A Multi-Institutional Study

Canter C, Naftel D, Caldwell R, Chinnock R, Pahl E, Fraizier E, Kirklin J, Boucek M, Morrow R, and the Pediatric Heart Transplant Study. Circulation. 1997 Jul 1;96(1):227-31.
December 1997
Publication
Infection after Pediatric Heart Transplantation: Results of a Multi-institutional Study

Schowengerdt K, Naftel D, Seib P, Pearce B, Addonizio L, Kirklin J, Morrow W, and the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 1997 Dec;16(12):1207-16.
December 1997
Publication
Outcome of Listing for Heart Transplantation in Infants Younger than Six Months: Predictors of Death and Interval to Transplantation

Morrow R, Naftel D, Chinnock R, Canter C, Boucek M, Zales V, McGiffin D, Kirklin J, and the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 1997 Dec;16(12):1255-66.
January 1, 1999
Second Major Form Revision
May 1999
Publication
Induction Immunotherapy in Pediatric Heart Transplant Recipients: A Multi-Center Evaluation

Boucek R, Naftel D, Boucek M, Chinnock R, Morrow R, Pahl E, DiSano S, and the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 1999 May;18(5):460-9.
June 2000
Publication
Survival after Listing for Cardiac Transplantation in Children

Morrow W, Frazier E, Naftel D. Prog Pediatr Cardiol. 2000 Jun 1;11(2): 99-105.
2001
Dr. William Robert Morrow named the inagural president of PHTS
2001
PHTS Bylaws created
March 2001
Publication
Death after Rejection with Severe Hemodynamic Compromise in Pediatric Heart Transplant Recipients: A Multi-Institutional Study

Pahl E, Naftel D, Canter C, Frazier E, Kirklin J, Morrow W, and the Pediatric Heart Transplant Study. J of Heart Lung Transplant. 2001 Mar;20(3):279-87.
November 2001
Dr. Charlie Canter becomes the 2nd president of PHTS
August 2003
Publication
Late Rejection Episodes More Than 1 Year after Pediatric Heart Transplantation: Risk Factors and Outcomes

Webber S, Naftel D, Parker J, Mulla N, Balfour I, Kirklin J, Morrow W, and the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 2003 Aug;22(8):869-75.
November 2003
Dr. Steve Webber becomes the 3rd president of PHTS
February 2004
Publication
Risk Factors For Recurrent Rejection in Pediatric Heart Transplantation: A Multicenter Experience

Chin C, Naftel D, Singh T, Blume E, Luikart H, Bernstein D, Gamberg P, Kirklin J, Morrow W, and for the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 2004 Feb;23(2):178-85.
January 1, 2005
Third Major Form Revision
May 2005
Publication
Fate of Infants with Hypoplastic Left Heart Syndrome Listed for Cardiac Transplantation: A Multi-center Study

Kichuk-Chrisant M, Naftel D, Hsu D, Drummond J, Chinnock R, Canter C, Boucek M, Boucek R, Hallowell S, Kirklin J, Morrow W, and the Pediatric Heart Transplant Study. J Heart Lung Transplant. 2005 May;24(5):576-82.
June 2005
Publication
The Impact and Outcome of Transplant Coronary Artery Disease in a Pediatric Population: A 9 Year Multi-Institutional Study

Pahl E, Naftel D, Kuhn M, Shaddy R, Morrow W, Canter C, Kirklin J, for the Pediatric Heart Transplant Study. J Heart Lung Transplant. 2005 Jun;24(6):645-51.
November 2005
Dr. Daphne Hsu becomes the 4th president of PHTS
January 2006
Publication
Lymphoproliferative Disorders After Paediatric Heart Transplantation: A Multi-institutional Study

Webber S, Naftel D, Fricker F, Olesnevich P, Blume E, Addonizio L, Kirklin J, Canter C, and the Pediatric Heart Transplant Study. Lancet. 2006 Jan 21;367(9506):233-9.
March 2006
Publication
Should Status II Patients Be Removed From the Pediatric Heart Transplant Waiting List? A Multi-Institutional Study

Kirklin J, Naftel D, Pearce F, Bartlett H, Rusconi P, White-Williams C, Robinson B. J Heart Lung Transplant. 2006 Mar;25(3):271-5.
May 2006
Publication
Lessons Learned from the Pediatric Heart Transplant Study

Hsu, D, Naftel D, Webber S, Morrow W, Canter C, Chinnock R, Clark M, Kirklin J. Congenit Heart Dis. 2006 May;1(3):54-62.
May 2006
Publication
Outcomes of Children Bridged to Heart Transplantation with Ventricular Assist Devices: A Multi-Institutional Study

Blume E, Naftel D, Bastardi H, Duncan B, Kirklin J, Webber S, and for the Peidatric Heart Transplant Study Investigators. Circulation. 2006 May 16;113(19): 2313-2319.
July 2006
Publication
Outcome of Listing for Cardiac Transplantation for Failed Fontan: A Multi-institutional Study

Bernstein D, Naftel D, Chin C, Addonizio L, Gamberg P, Blume E, Hsu D, Canter C, Kirklin J, Morrow W, and the Pediatric Heart Transplant Study Group. Circulation. 2006 Jul 25;114(4):273-80.
October 2006
Publication
Hyperlipidemia in Children after Heart Transplantation

Singh TP Naftel D, Webber S, Dupuis J, Chin C, Spicer R, Schowengerdt K, Ring W, Morrow R, and the Pediatric Heart Transplant Study. J Heart Lung Transplant. 2006 Oct;25(10): 1199-205.
December 2006
Publication
Cardiac Re-transplantation in Pediatrics: A Multi-Institutional Study

Chin C, Naftel D, Pahl E, Shankel T, Clark M, Gamberg P, Kirklin J, Webber S, and the Pediatric Heart Transplant Study. The Journal of Heart Lung Transplantation 2006 Dec;25(12):1420-24.
December 2006
Publication
Disparate Distribution of 16 Candidate Single Nucleotide Polymorphisms Among Racial and Ethnic Groups of Pediatric Heart Transplant Patients.
(In collaboration with SCCOR)

Girnita D, Webber S, Ferrell R, Burckart G, Brooks M, McDade K, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Girnita A, Zeevi A. Transplant. 2006 Dec 27;82(12):1774-80
2007
Publication
ISHLT Monograph Series Volume 2: Pediatric Heart Transplantation

Canter C and Kirklin J, editors. ISHLT Monograph Series: Pediatric Heart Transplantation. Philadelphia: Elsevier Inc; 2007. 2 vol.
2007
Publication
Recipient Characteristics

Canter C, Naftel D. Recipient Characteristics In: Fine R, Webber S, Harmon W, Kelly D, Olthoff K, editors. Pediatric Solid Organ Transplantation, Second Edition. Oxford, UK: Blackwell Publishing, 2007. p. 259-64.
May 2007
Publication
Sudden Death Prior to Pediatric Heart Transplantation: Would Implantable Defibrillators Improve Outcome?

Rhee E, Canter C, Basile S, Webber S, Naftel D. J Lung Heart Transplant. 2007 May;26(5):447-52.
November 2007
Dr. Elizabeth (Betsy) Blume becomes the 5th president of PHTS
June 2008
Publication
Genetic Polymorphisms Impact the Risk of Acute Rejection in Pediatric Heart Transplantation: A Multi-Institutional Study
(In collaboration with SCCOR)

Girnita D, Brooks M, Webber S, Burckart G, Ferrell R, Zdanowicz G, DeCroo S, Smith L, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin J, Ranganathan S, Naftel D, Girnita AL, Zeevi A. Transplant. 2008 Jun 15;85(11):1632-9.
February 9, 2009
Susanna Lenderman joins the PHTS team at the Data Coordinating Center.
June 2009
Publication
Genotypic variation and phenotypic characterization of granzyme B gene polymorphisms
(In collaboration with SCCOR)

Girnita D, Webber S, Brooks M, Ferrell R, Girnita A, Burckart G, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin J, Naftel D, Zeevi A. Transplant. 2009 Jun 27;87(12):1801–6.
July 2009
Publication
The Effect of Age, Diagnosis, and Previous Surgery in Children and Adults Undergoing Heart Transplantation for Congenital Heart Disease
(In collaboration with CTRD)

Lamour J, Kanter K, Naftel D, Chrisant M, Morrow W, Clemson B, Kirklin J, on behalf of the CTRD (Cardiac Transplant Registry Database) and the PHTS (Pediatric Heart Transplant Study). J Am Coll Cardiol. 2009 Jul 7;54(2):160-5.
September 2009
Publication
Association of Left Ventricular Dilation at Listing for Heart Transplant With Postlisting and Early Posttransplant Mortality in Children With Dilated Cardiomyopathy
(In collaboration with PCMR)

Singh T, Sleeper L, Lipshultz S, Cinar A, Canter C, Webber S, Bernstein D, Pahl E, Alvarez A, Wilkinson J, Towbin J, Colan S. Circulation. 2009 September 28;2: 591-598
November 2009
Dr. Anne Dipchand becomes the 6th president of PHTS
December 2009
Publication
Does Cytomegalovirus Serology Impact Outcome After Pediatric Heart Transplantation?

Mahle W, Foushee M, Naftel D, Alejos J, Caldwell R, Uzark K, Berg A, Kanter K, and the Pediatric Heart Transplant Study Group.J Heart Lung Transplant. 2009 Dec;28(12):1299-305.
December 2009
Publication
Outcomes of Children With Cardiomyopathy Listed for Transplant: A Multi-institutional Study

Dipchand A, Naftel D, Feingold B, Spicer R, Yung D, Kaufman B, Kirklin J, Allain-Rooney T, Hsu D, and Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2009 Dec;28(12):1312-21.
December 2009
Publication
Outcome of Pediatric Patients With Dilated Cardiomyopathy Listed for Transplant: A Multi-institutional Study

Kirk R, Naftel D, Hoffman T, Almond C, Boyle G, Caldwell R, Kirklin J, White K, Dipchand A, and Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2009 Dec;28(12):1322-8.
December 2009
Publication
Outcomes of Pediatric Patients With Hypertrophic Cardiomyopathy Listed for Transplant

Gajarski R, Naftel D, Pahl E, Alejos J, Pearce F, Kirklin J, Zamberlan M, Dipchand A, and Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2009 Dec;28(12):1329-34.
December 2009
Publication
Outcomes of Children With Restrictive Cardiomyopathy Listed for Heart Transplant: A Multi-institutional Study

Zangwill S, Naftel D, L’Ecuyer T, Rosenthal D, Robinson B, Kirklin J, Stendahl G, Dipchand A, for the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2009 Dec;28(2):1335-40.
January 1, 2010
Fourth Major Form Revision
March 2010
Publication
Rejection with hemodynamic compromise in the current era of pediatric heart transplantation: A multi-institutional study

Everitt M, Pahl E, Schechtman K, Zheng J, Ringewald J, L’Ecuyer T, Naftel D, Kirklin J, Blume E, Bullock E, Canter C, for the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2010 Mar;30(3):282-8.
June 2010
Publication
Decline in Rejection in the First Year after Pediatric Cardiac Transplantation: A multi-institutional study

Gossett J, Canter C, Zheng J, Schechtman K, Blume E, Rodgers S, Naftel D, Kirklin J, Scheel J, Fricker F, Kantor P, Pahl E, and Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2010 Jun;29(6):625-32.
July 22, 2010
PHTS Foundation incorporated as a 501(c)3 Non-Profit Organization
September 2010
Publication
Association of Race and Socioeconomic Position with Outcomes in Pediatric Heart Transplant Recipients

Singh T, Naftel D, Addonizio L, Mahle W, Foushee M, Zangwill S, Blume E, Kirklin J, Singh R, Johnston J, Chinnock R. Am J Transplant. 2010 Sep;10(9):2116-23
Novmeber 2010
Publication
Outcomes of pediatric heart transplant recipients transitioned to adult care: An exploratory study

McBride M, Foushee M, Brown R, Ewald G, Canter C. J Heart Lung Transplant. 2010 Nov;29(11):1309-10.
November 1, 2010
Inaugural meeting of the PHTS Foundation Board of Directors
  • Dr. Anne Dipchand elected as Chair
  • Dr. William “Bill” Mahle elected as Vice Chair
  • Dr. Elfriede “Elfi” Pahl elected as Secretary/Treasurer
  • Articles of Incorporation Adopted
November 14, 2010
PHTS Foundation appoints Craig Collum as Executive Director
December 2010
Publication
Association of Genetic Polymorphisms and Risk of Late Post-Transplant Infection in Pediatric Heart Recipients
(In collaboration with SCCOR)

Ohmann E, Brooks M, Webber S, Girnita D, Ferrell R, Burckart G, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin J, Naftel D, Zeevi A. J Heart Lung Transplant. 2010 Dec;29(12):1342-5.
February 2011
Publication
Minimizing Infection and Rejection Death: Clues Acquired from 19 Years of Multi-institutional Cardiac Transplantation Data

George J, Taylor D, Blume E, Kirklin J, Naftel D, Brown R, Dipchand A, McGiffin D, Pamboukian S,Tallaj J. J Heart Lung Transplant. 2011 Feb;30(2):151-7.
March 2011
Publication
Infection and malignancy after pediatric heart transplantation: The role of induction therapy

Gajarski R, Blume E, Urshel S, Schechtman K, Zheng J, West L, Altamirano L, Miyamoto S, Naftel D, Kirklin J, Zamberlan M, Canter C, for the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2011 Mar;30(3):299-308.
March, 2011
DeAnna (Beckham) Archer joins the PHTS team at the Data Coordinating Center.
June 2011
Publication
Gene Polymorphisms Impact The Risk Of Rejection With Hemodynamic Compromise: A Multicenter Study
(In collaboration with SCCOR)

Girnita D, Ohmann E, Brooks M, Webber S, Burckart G, Ferrell R, Ranganathan S, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin J, Naftel D, Zeevi A. Transplant. 2011 Jun 27;91(12):1326-32.
July 2011
Publication
The Impact of Heart Failure Severity at Time of Listing for Cardiac Transplantation on Survival in Pediatric Cardiomyopathy
(In collaboration with PCMR)

Larsen R, Canter C, Naftel D, Tresler M, Rosenthal D, Blume E, Mahle W, Yung D, Morrow R, Orav J, Wilkinson J, Towbin J, Lipshultz S. J Heart Lung Transplant. 2011 Jul;30(7):755-60.
August 2011
Publication
Invasive Fungal Infections in Pediatric Heart Transplant Recipients: Incidence, Risk Factors, and Outcomes

Zaoutis T, Webber S, Naftel D, Christant M, Kaufman B, Pearce F, Spicer R, Dipchand A on behalf of the Pediatric Heart Transplant Study Investigators. Pediatr Transplant. 2011 Aug;15(5):465-9.
September 2011
Publication
Outcomes Following Listing for Primary Transplantation for Infants with Unoperated Non-Hypoplastic Left Heart Syndrome (Non-HLHS) Congenital Heart Disease: A Multi-Institutional Study

Guleserian K, Schechtman K, Zheng J, Edens R, Jacobs J, Mahle W, Emerson S, Naftel D, Kirklin J, Blume E, Canter C. J Heart Lung Transplant. 2011 Sep;30(9):1023-32.
November 2011
Publication
Allosensitization and Outcomes in Pediatric Heart Transplantation

Mahle W, Tresler M, Edens E, Rusconi P, George J, Naftel D, Shaddy R, and the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 2011 Nov;30(11):1221-7.
November 2011
Publication
Risk Factors for Late Renal Dysfunction after Pediatric Heart Transplantation: A Multi-institutional Study

Feingold B, Zheng J, Law Y, Morrow W, Hoffman T, Schechtman K, Dipchand A, Canter C, and the Pediatric Heart Transplant Study Investigators. Pediatr Transplant. 2011 Nov;15(7):699-705.
November 2011
Dr. William (Bill) Mahle becomes the 7th president of PHTS
December 2011
Publication
Sudden Death after Pediatric Heart Transplantation: Analysis of data from the Pediatric Heart Transplant Study Group

Daly K, Chakravarti S, Tresler M, Naftel D, Blume B, Dipchand A, and Almond C, for the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2011 Dec;30(12):1395-402.
December 2011
Publication
Outcomes of Pneumocystis jiroveci pneumonia infections in Pediatric Heart Transplant Recipients

Ng B, Dipchand A, Naftel D, Rusconi P, Boyle G, Zaoutis T, Edens E. Pediatr Transplant. 2011 Dec;15(8):844-8.
February 2012
Publication
Comparison of risk factors and outcomes for pediatric patients listed for heart transplantation after bidirectional Glenn and after Fontan: an analysis from the Pediatric Heart Transplant Study

Kovach J, Blume E, Naftel D, Pearce B, Tresler M, Edens E, Shuhaiber J, Blume E, Fynn-Thompson F, Kirklin J, Zangwill S. J Heart Lung Transplant. 2012 Feb;31(2):133-9.
February 2012
Publication
ABO-incompatible Heart Transplantation: Analysis of the Pediatric Heart Transplant Study (PHTS) Database

Henderson H, Canter C, Mahle W, Dipchand A, LaPorte K, Schechtman K, Zheng J, Asante-Korang A, Singh R, Kanter K. J Heart Lung Transplant. 2012 Feb;31(2):173-9.
May 2012
Publication
Early survival after heart transplant in young infants is lowest after failed single-ventricle palliation: a multi-institutional study

Everitt M, Boyle G, Schechtman K, Zheng J, Bullock E, Kaza A, Dipchand A, Naftel D, Kirklin J, Canter C, for the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2012 May;31(5):509-16.
August 2012
Publication
Early Predictors of Survival to and After Heart Transplantation in Children with Dilated Cardiomyopathy
(In collaboration with PCMR)

Pietra B, Kantor P, Bartlett H, Chin C, Canter C, Larsen R, Edens E, Colan S, Towbin J, Lipshulz S, Kirklin J, Naftel D, Hsu D . Circulation. 2012 Aug 28;126(9):1079-86.
September 2012
Publication
Has Late Rejection Decreased in Pediatric Heart Transplantation in the Current Era? A Multi-institutional Study

Ameduri R, Zheng J, Schechtman K, Hoffman T, Gajarski R, Chinnock R, Naftel D, Kirklin J, Dipchand A, Canter C. J Heart Lung Transplant. 2012 Sep;31(9):980-6.
September 2012
Publication
Renal Function and genetic polymorphisms in pediatric heart transplant recipients
(In collaboration with SCCOR)

Feingold B, Brooks M, Zeevi A, Ohmann E, Burckart G, Ferrell R, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin J, Naftel D, Webber S. J Heart Lung Transplant. 2012 Sep;31(9):1003-8.
November 2012
Publication
A 16-Year Multi-Institutional Study of the Role of Age and EBV Status on PTLD Incidence Among Pediatric Heart Transplant Recipients

Chinnock R, Webber S, Dipchand A, Brown R, George J. American Journal of Transplant. 2012 Nov; 12: 3061-3068.
January 2013
PHTS Releases “Pediatric Heart Transplant: A Guide for Patients and Families”
March 2013
Publication
Outcomes of Cardiac Transplantation in Single Ventricle Patients with Plastic Bronchitis—a Multi-Center Report

Gossett J, Almond C, Kirk R, Zangwill S, Richmond M, Kantor P, Tresler M, Lenderman S, Naftel D, Matthews K, Pahl E. J Am Coll Cardiol. 2013 Mar 5;61(9):985-6.
March 2013
Publication
Ten years of Pediatric Heart Transplantation: A Report from the Pediatric Heart Transplant Study

Dipchand A, Kirk R, Mahle W, Tresler M, Naftel D, Pahl E, Miyamoto S, Blume E, Guleserian K, White-Williams C, Kirklin J. Pediatr Transplantation 2013 Mar: 17: 99-111
November 2013
Publication
Outcomes of fetal listed patients awaiting heart transplantation

Conway J, Chrisant M, West L, Rebecca A, Alejos J, Lamour J, Das B, Gilbert D, Tresler M, Naftel D, Miyamoto S. 2013 Nov;17(7):653-60.
November 17, 2013
20th Anniversary Gala
PHTS celebrated 20 years of data collection on the evening of Sunday, November 17, 2013 at the T. Boone Pickens Biomedical Building in Dallas, Texas.
Dr. Morrow, Dr. Kirklin, and Dr. Naftel receive the “Founding Fathers Award”.
November 2013
Dr. Robert Gajarski becomes the 8th president of PHTS
December 2013
Publication
Donors’ characteristics and impact on outcomes in pediatric heart transplant recipients

Conway J, Chin C, Kemna M, Burch M, Barnes A, Tresler M, Scheel J, Naftel D, Beddow K, Allain-Rooney T, Dipchand A. Pediatr Transplantation 2013 Dec:17
January 2014
Publication
Multi-institutional Study of Outcomes After Pediatric Heart Transplantation: Candidate Gene Polymorphism Analysis of ABCC2
(In collaboration with SCCOR)

Burckart G, Figg W, Brooks M, Green D, Troutman S, Ferrell R, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin J, Naftel D, Price D, Sissung T, Girnita D, Zeevi A, Webber S. J Pediatr Pharmacol Ther. 2014 Jan;19(1):16-24.
May 2014
Publication
Hypoalbuminemia and poor growth predict worse outcomes in pediatric heart transplant recipients

Castleberry C, White-Williams C, Naftel D, Tresler MA, Pruitt E, Miyamoto SD, Murphy D, Spicer R, Bannister L, Schowengerdt K, Gilmore L, Kaufman B, Zangwill S. Pediatr Transplantation 2014 May: 18: 280-287.
March 2015
Publication
Predicting Graft Loss by 1 Year in Pediatric Heart Transplantation Candidates: An Analysis of the Pediatric Heart Transplant Study Database

Schumacher KR, Almond C, Singh TP, Kirk R, Spicer R, Hoffman TM, Hsu D, Naftel DC, Pruitt E, Zamberlan M, Canter CE, Gajarski RJ. Circulation 2015 Mar: 131: 890-898.
March 2015
Publication
Elevated pre-transplant pulmonary vascular resistance is not associated with mortality in children without congenital heart disease: a multicenter study

Richmond ME, Law YM, Das BB, Everitt MD, Kukreja M, Naftel DC, Kemna MS, Henderson HT, Beddows K, Fricker FJ, Mahle WT, and on the behalf of the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant 2015: Mar; 34(3):448-456.
May 31, 2015
Dr. David Naftel retires from UAB and steps down as the PHTS DCC director. Dr. James Kirklin becomes the new director of the PHTS DCC.
August 2015
Publication
Maintenance Steroid Use at 30 Days Post-Transplant and Outcomes of Pediatric Heart Transplantation: A Propensity Matched Analysis of the Pediatric Heart Transplant Study (PHTS) Database

Auerbach S, Kukreja M, Gilbert D, Bastardi H, Feingold B, Knecht K, Kaufman B, Brown R, Miyamoto S. J Heart Lung Transplant 2015: Aug, 34 (8): 1066-1072.
August 2015
Publication
Improved Detection of Cardiac Allograft Vasculopathy: A Multi-Institutional Analysis of Functional Parameters in Pediatric Heart Transplant Recipients

Kindel SJ, Law YM, Chin C, Burch M, Kirklin JK, Naftel DC, Pruitt E, Carboni MP, Arens A, Atz AM, Dreyer WJ, Mahle WT, Pahl E. J Am Coll Cardiol 2015: Aug, 66 (5): 547-557.
September 2015
Publication
Outcomes after percutaneous coronary artery revascularization procedures for cardiac allograft vasculopathy in pediatric heart transplant recipients: A multi-institutional study

Jeewa A, Chin C, Pahl E, Atz AM, Carboni MP, Pruitt E, Naftel DC, Rodriguez R, Dipchand AI, and the Pediatric Heart Transplant Study (PHTS) Investigators. J Heart Lung Transplant 2015: Sep, 34 (9): 1163-1168.
September 2015
Publication
Fontan-associated protein-losing enteropathy and heart transplant: A pediatric Heart Transplant Study analysis

Schumacher KR, Gossett J, Guleserian K, Naftel DC, Pruitt E, Dodd D, Carboni M, Lamour J, Pophal S, Zamberlan M, Gajarski RJ. J Heart Lung Transplant 2015: Sep 34 (9): 1169-1176.
September 2015
Publication
Extracorporeal Membrane Oxygenation as a Bridge to Pediatric Heart Transplantation: Effect on Post-Listing and Post-Transplantation Outcomes

Dipchand AI, Mahle WT, Tresler M, Naftel DC, Almond C, Kirklin JK, Pruitt E, Webber SA, and the Pediatric Heart Transplant Study Investigators. Circ Heart Fail 2015: Sep 8 (5): 960-969.
October 7, 2015
Launch of Web Based Data Entry System
Data entry transitioned from paper form submission to online submission.
November 2015
Dr. Melanie Everitt becomes the 9th president of PHTS
January 2016
Publication
Outcomes of heart transplantation in children with hypoplastic left heart syndrome previously palliated with the Norwood procedure.

Alsoufi B, Mahle WT, Manlhiot C, Deshpande S, Kogon B, McCrindle B, Kanter K and the Pediatric Heart Transplant Study Investigators. The Journal of Thoracic and Cardiovascular Surgery, 2016-01-01, Volume 151, Issue 1, Pages 167-175.e2
March 2016
Publication
Impact of initial Norwood shunt type on young hypoplastic left heart syndrome patients listed for heart transplant: A multi-institutional study

Carlo W, West S, McCulloch M, Naftel D, Pruitt E, Kirklin JK, Hubbard M, Molina K, Gajarski R, and the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant 2016: March 35 (3): 301-305.
April 2016
Publication
Statin therapy is not associated with improved outcomes after heart transplantation in children and adolescents.

Greenway SC, Butts R, Naftel DC, Pruitt E, Kirklin JK, Urschel S, Knecht K, Law Y, and the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2016 Apr; 35 (4):457-65.
April 2016
Publication
Left ventricular non-compaction cardiomyopathy in children listed for heart transplant: Analysis from the Pediatric Heart Transplant Study Group

Lal A, Pruitt E, Hong B, Lin K, Feingold B, and the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2016 Apr; 35 (4):540-542.
December 2016
Publication
A multi-institutional evaluation of antibody-mediated rejection utilizing the Pediatric Heart Transplant Study database: Incidence, therapies and outcomes

Thrush PT, Pahl E, Naftel DC, Pruitt E, Everitt MD, Missler H, Zangwill S, Burch M, Hoffman TM, Butts R, and Mahle WT. J Heart Lung Transplant. 2016 Dec, 35 (12): 1497-1504.
April 2017
Publication
Use of sirlomus in pediatric heart transplant patients: A multi-institutional study from the Pediatric Heart Transplant Study Group

Rosanno JW, Jefferies JL, Pahl E, Naftel DC, Pruitt E, Lupton K, Dreyer WJ, Chinnock R, Boyle G, Mahle WT, on behalf of the Pediatric Heart Transplant Study Investigators. J Heart Lung Transplant. 2017 Apr, 36 (4): 427-433
April 2017
Publication
Impact of age on incidence and prevalence of moderate-to-severe cellular rejection detected by routine surveillance biopsy in pediatric heart transplantation.

Zinn MD, Wallendorf MJ, Simpson KE, Osborne AD, Kirklin JK, Canter CE. J Heart Lung Transplant. 2017 Apr, 36 (4) 451-456.
April 2017
Publication
Fontan Patient Survival After Pediatric Heart Transplant Has Improved in the Current Era

Simpson K, Pruitt E, Naftel D, Kirklin J, Singh R, Barnes A, Edens E, and Canter C. The Annals of Thoracic Surgery. 2017 Apr, 103 (4) 1315 – 1320.
June 2017
Publication
The Influence of Race and Common Genetic Variations on Outcomes After Pediatric Heart Transplantation
(In collaboration with SCCOR)

Green DJ, Brooks MM, Burckart GJ, Chinnock RE, Canter C, Addonizio LJ, Bernstein D, Kirklin JK, Naftel DC, Girnita DM, Zeevi A, Webber SA. Am J Transplant. 2017 Jun;17(6):1525-1539
August 2017
Publication
Cancer Recurrence and Mortality after Pediatric Heart Transplantation for Anthracycline Cardiomyopathy: A Report from the Pediatric Heart Transplant Study (PHTS) Group

Bock M, Pruitt E, Pahl E, Rusconi P, Boyle GJ, Parent JJ, Twist C, Kirklin JK, Bernstein D. Pediatric Transplantation. 2017 Aug, 21 (5) e12923.
September 2017
Publication
Bacterial infections following pediatric heart transplantation: Epidemiology, risk factors, and outcomes

Rostad CA, Wehrheim K, Kirklin JK, Naftel D, Pruitt E, Hoffman TM, L’Ecuyer T, Berkowitz K, Mahle WT, Scheel JN. J Heart Lung Transplant. 2017 Sept, 36 (9) 996 – 1003.
October 2017
Publication
Haemodynamic Profiles of Children with End-Stage Heart Failure

Chen S, Dykes JC, McElhinney DB, Gajarski RJ, Shin AY, Hollander SA, Everitt ME, Price JF, Thiagarajan RR, Kindel SJ, Rossano JW, Kaufman BD, May LJ, Pruitt E, Rosenthal DN, Almond CS, European Heart Journal. 2017 Oct, 38 (38) 2900-2909
November 2017
Dr. Marc Richmond becomes the 10th president of PHTS
2018
Dr. Ryan Cantor joins the PHTS team at the Data Coordinating Center.
2018
Devin Koehl joins the PHTS team at the Data Coordinating Center.
February 2018
Sandre McNeal joins the PHTS team at the Data Coordinating Center.
February 2018
Publication
The impact of flow PRA on outcome in pediatric heart recipients in modern era: An analysis of the Pediatric Heart Transplant Study database

Das BB, Pruitt E, Molina K, Ravekes W, Auerbach S. Savage A, Knox L, Kirklin JK, Naftel DC, Hsu D., Pediatr Transplant 2018 Feb, 22(1).
March 1, 2018
PHTS Study becomes PHTS Society
The PHTS membership votes to change the name of the Pediatric Heart Transplant Study to transition to the Pediatric Heart Transplant Society.
April 2018
Publication
Development and Validation of a Major Adverse Transplant Event (MATE) Score to Predict Late Graft Loss in Pediatric Heart Transplantation

Almond CS, Rossano JW, Hoen H, Castleberry C, Auerbach S, Yang L, Lal AK, Everitt MD, Pahl E, Fenton M, Hollander SA, McElhinney DB, Rosenthal DN, Daly KP, Desai M. J Heart Lung Transplant 2018 Apr, 37 (4) 441-450
April 2018
Publication
Risk stratification to determine the impact of induction therapy on survival, rejection, and adverse events after Pediatric Heart Transplant: A multi-institutional study

Castleberry CD, Pruitt E, Ameduri R, Schowengerdt K, Edens E, Hagin N, Kirklin JK, Naftel D, Urschel S, J Heart Lung Transplant 2018 Apr, 37(4) 458-466
May 2018
Publication
Impact of routine Surveillance biopsy intensity on the diagnosis of moderate to severe cellular rejection and survival after pediatric heart transplantation

Matthew Zinn, Michael Wallendorf, Kathleen Simpson, Ashley Osborne, James Kirklin, Charles Canter.Pediatr Transplant 2018 May, 22(3).
June 2018
Publication
Post-transplant outcomes in pediatric VAD patients: A Pedimacs-Pediatric Heart Transplant Study linkage analysis
(In collaboration with Pedimacs)

Sutcliffe DL, Pruitt E, Cantor RS, Godown J, Lane J, Turrentine MW, Law SP, Lantz JL, Kirklin JK, Bernstein D, Blume ED, J Heart Lung Transplant. 2018 June, 37 (6) 715-722.
July 2018
Publication
Ventricular Assist Device Support as a Bridge to Pediatric Heart Transplantation: A Quarter Century of Evolution

Anne I Dipchand, Richard Kirk, David C Naftel, Elizabeth Pruitt, Elizabeth D. Blume, Robert Morrow, David Rosenthal, Scott Auerbach, Marc E. Richmond, James K. Kirklin for the Pediatric Heart Transplant Study Investigators. Journal of the American College of Cardiology. 2018 July, 72 (4) 402-415
August 20, 2018
New Society Logo
The Pediatric Heart Transplant Society held a logo competition among the membership for a new logo. The membership voted and the society adopted a new logo to represent the PHTS Registry and the PHTS Foundation
September 2019
PHTS Releases Updated Guidebook “Pediatric Heart Transplant: A Guide for Patients and Families”
March 2019
Publication
Cardiac Allograft Vasculopathy and Graft Failure in Pediatric Heart Transplant Recipients After Rejection with Severe Hemodynamic Compromise

Jake Kleinmahon, Jane Gralla, Richard Kirk, Scott Auerbach, Heather Henderson, Gonzalo Wallis, Karthik Ramakrishnan, Rakesh Singh, Randall Caldwell, Melanie Everitt J Heart Lung Transplant. 2019 Mar;38(3):277-284.
April 3, 2019
25th Anniversary Gala
PHTS celebrated 25 years of data collection on the evening of Wednesday, April 3, 2019 at Howl at the Moon in Orlando, Florida.
April 2019
Publication
Long-term outcomes after transplantation after support with a pulsatile pediatric ventricular assist device

Aamir Jeewa, Michiaki Imamura, Charles Canter, Robert Niebler, Christina VanderPluym, David Rosenthal, James Kirklin, Ryan Cantor, Margaret Tresler, David Michael McMullan, Victor Morell, Mark Turrentine, Rebecca Ameduri, Khanh Nguyen, Kirk Kanter, Jennifer Conway, Robert Gajarski, and Charles Fraser. J Heart Lung Transplant. 2019 Apr;38(4):449-455.
May 2019
Publication
Characteristics, risks, and outcomes of post-transplant lymphoproliferative disease >3 years after pediatric heart transplant: A multicenter analysis

Shawn West, Josh Friedland-Little, Kenneth Schowengerdt, David Naftel, Elizabeth Pruitt Freeze, Kelli Smith, Simon Urschel, Marian Michaels, James Kirklin, Brian Feingold. Clin Transplant. 2019 May;33(5)
August 2019
Publication
Renal injury and recovery in pediatric patients after ventricular assist device implantation and cardiac transplant
(In collaboration with Pedimacs)

Seth Hollander, Ryan Cantor, Scott Sutherland, Devin Koehl, Elizabeth Pruitt, Nancy McDonald, James Kirklin, William Ravekes, Rebecca Ameduri, Maryanne Chrisant, Timothy Hoffman, Irene Lytrivi, Jennifer Conway. Pediatr Transplant 2019 Aug;23(5)
August 2019
Publication
New onset diabetes after pediatric heart transplantation: A review of the Pediatric Heart Transplant Study

Joshua Sparks, Ryan Cantor, Elizabeth Pruitt, James Kirklin, Michael Carboni, William Dreyer, Steven Kindel, Thomas Ryan, Robert Morrow. Pediatr Transplant 2019 Aug;23(5)
November 2019
Dr. Jennifer Conway becomes the 11th president of PHTS
February 2020
PHTS Releases Spanish Version of Guidebook “Pediatric Heart Transplant: A Guide for Patients and Families”
June 3, 2020
First PHTS Live Session
Topic: ISHLT Guidelines on Donor Acceptability
June 5, 2020
Dr. James Kirklin guest on PediHeart Podcast
Pediheart: Pediatric Cardology Today Postcast with Robert. H. Pass, MD

Dr. Pass interviews Dr. James Kirklin on Pediatric Heart Transplant through the lens of the Pediatric Heart Transplant Society
April 2020
Publication
Educational and learning morbidity in pediatric heart transplant recipients: A pediatric heart transplant society study

Micah S. Brosbe, Lydia K. Wright, Ryan Cantor, William J. Dreyer, Sonya Kirmani, Margaret Knight, Stephanie J. Nakano, Steven J. Kindel, Thomas D. Ryan, James K. Kirklin, Shriprasad R. Deshpande. Pediatr Transplant. 2020; 24:e13711.
July 2020
Publication
A current era analysis of ABO incompatible listing practice and impact on outcomes in young children requiring heart transplantation

Simon Urschel, Marie McCoy, Ryan S Cantor, Devin A Koehl, Warren A Zuckerman, Anne I Dipchand, Zdenka Reinhardt, Kirk R Kanter, Jean A Ballweg, Joshua Sparks, James K Kirklin, Waldemar F Carlo. J Heart Lung Transplant . 2020 Jul;39(7):627-635.
August 2020
Publication
Surveillance for cardiac allograft vasculopathy: Practice variations among 50 pediatric heart transplant centers

Deipanjan Nandi, Clifford Chin, Kurt R Schumacher, Matthew Fenton, Rakesh K Singh, Kimberly Y Lin, Jennifer Conway, Ryan S Cantor, Devin A Koehl, Jacqueline M Lamour, James K Kirklin, Elfriede Pahl. J Heart Lung Transplant. 2020 Aug 8;S1053-2498(20)31692-2
November 2020
Publication
Survival After Heart Transplant Listing for Infants on Mechanical Circulatory Support

Jennifer Conway, MD; Ryan Cantor, PhD; Devin Koehl, BS; Robert Spicer, MD; Dipankar Gupta, MD; Michael McCulloch , MD; Alfred Asante-Korang, MD; Dean T. Eulrich, PhD; James K. Kirklin, MD; Elfriede Pahl, MD. J Am Heart Assoc. 2020 Nov 3;9(21):e011890. doi: 10.1161/JAHA.118.011890. Epub 2020 Oct 20.